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Signaling Overlap between the Golgi Stress Response and Cysteine Metabolism in Huntington’s Disease
Huntington’s disease (HD) is caused by expansion of polyglutamine repeats in the protein huntingtin, which affects the corpus striatum of the brain. The polyglutamine repeats in mutant huntingtin cause its aggregation and elicit toxicity by affecting several cellular processes, which include dysregu...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465517/ https://www.ncbi.nlm.nih.gov/pubmed/34573100 http://dx.doi.org/10.3390/antiox10091468 |