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Signaling Overlap between the Golgi Stress Response and Cysteine Metabolism in Huntington’s Disease

Huntington’s disease (HD) is caused by expansion of polyglutamine repeats in the protein huntingtin, which affects the corpus striatum of the brain. The polyglutamine repeats in mutant huntingtin cause its aggregation and elicit toxicity by affecting several cellular processes, which include dysregu...

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Detalles Bibliográficos
Autor principal: Paul, Bindu D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465517/
https://www.ncbi.nlm.nih.gov/pubmed/34573100
http://dx.doi.org/10.3390/antiox10091468