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Identification and Characterization of an Affimer Affinity Reagent for the Detection of the cAMP Sensor, EPAC1

An exchange protein directly activated by cAMP 1 (EPAC1) is an intracellular sensor for cAMP that is involved in a wide variety of cellular and physiological processes in health and disease. However, reagents are lacking to study its association with intracellular cAMP nanodomains. Here, we use non-...

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Detalles Bibliográficos
Autores principales: Buist, Hanna K., Luchowska-Stańska, Urszula, van Basten, Boy, Valli, Jessica, Smith, Brian O., Baillie, George S., Rickman, Colin, Ricketts, Bryon, Davidson, Alex, Hannam, Ryan, Sunderland, Joanne, Yarwood, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465552/
https://www.ncbi.nlm.nih.gov/pubmed/34571955
http://dx.doi.org/10.3390/cells10092307