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Identification and Characterization of an Affimer Affinity Reagent for the Detection of the cAMP Sensor, EPAC1
An exchange protein directly activated by cAMP 1 (EPAC1) is an intracellular sensor for cAMP that is involved in a wide variety of cellular and physiological processes in health and disease. However, reagents are lacking to study its association with intracellular cAMP nanodomains. Here, we use non-...
Autores principales: | Buist, Hanna K., Luchowska-Stańska, Urszula, van Basten, Boy, Valli, Jessica, Smith, Brian O., Baillie, George S., Rickman, Colin, Ricketts, Bryon, Davidson, Alex, Hannam, Ryan, Sunderland, Joanne, Yarwood, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465552/ https://www.ncbi.nlm.nih.gov/pubmed/34571955 http://dx.doi.org/10.3390/cells10092307 |
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