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Loss of Ubiquitin Carboxy-Terminal Hydrolase L1 Impairs Long-Term Differentiation Competence and Metabolic Regulation in Murine Spermatogonial Stem Cells

Spermatogonia are stem and progenitor cells responsible for maintaining mammalian spermatogenesis. Preserving the balance between self-renewal of spermatogonial stem cells (SSCs) and differentiation is critical for spermatogenesis and fertility. Ubiquitin carboxy-terminal hydrolase-L1 (UCH-L1) is hi...

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Detalles Bibliográficos
Autores principales: Alpaugh, Whitney F., Voigt, Anna L., Dardari, Rkia, Su, Lin, Al Khatib, Iman, Shin, Wisoo, Goldsmith, Taylor M., Coyle, Krysta M., Tang, Lin A., Shutt, Timothy E., Klein, Claudia, Biernaskie, Jeff, Dobrinski, Ina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465610/
https://www.ncbi.nlm.nih.gov/pubmed/34571914
http://dx.doi.org/10.3390/cells10092265