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Medroxyprogesterone Acetate (MPA) Enhances HIV-1 Accumulation and Release in Primary Cervical Epithelial Cells by Inhibiting Lysosomal Activity

Medroxyprogesterone acetate (MPA) is one of the most widely used contraceptives in the world. Epidemiologic studies have uncovered a possible link between the use of MPA and an increased risk of HIV-1 transmission. However, the understanding of the mechanism is still limited. Our previous publicatio...

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Detalles Bibliográficos
Autores principales: Jia, Xiangxu, Shao, Qiujia, Chaudhry, Ahsen R., Kinlock, Ballington L., Izban, Michael G., Zhang, Hong-Ying, Villalta, Fernando, Hildreth, James E. K., Liu, Bindong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465616/
https://www.ncbi.nlm.nih.gov/pubmed/34578224
http://dx.doi.org/10.3390/pathogens10091192