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Semaphorin 3A—Glycosaminoglycans Interaction as Therapeutic Target for Axonal Regeneration

Semaphorin 3A (Sema3A) is a cell-secreted protein that participates in the axonal guidance pathways. Sema3A acts as a canonical repulsive axon guidance molecule, inhibiting CNS regenerative axonal growth and propagation. Therefore, interfering with Sema3A signaling is proposed as a therapeutic targe...

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Detalles Bibliográficos
Autores principales: Pérez, Yolanda, Bonet, Roman, Corredor, Miriam, Domingo, Cecilia, Moure, Alejandra, Messeguer, Àngel, Bujons, Jordi, Alfonso, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465649/
https://www.ncbi.nlm.nih.gov/pubmed/34577606
http://dx.doi.org/10.3390/ph14090906