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A Novel Competitive Binding Screening Assay Reveals Sennoside B as a Potent Natural Product Inhibitor of TNF-α

Natural products (NPs) have played a significant role in drug discovery for diverse diseases, and numerous attempts have been made to discover promising NP inhibitors of tumor necrosis factor α (TNF-α), a major therapeutic target in autoimmune diseases. However, NP inhibitors of TNF-α, which have th...

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Detalles Bibliográficos
Autores principales: Peng, Lei, Durai, Prasannavenkatesh, Park, Keunwan, Pyo, Jeong Joo, Choi, Yongsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465676/
https://www.ncbi.nlm.nih.gov/pubmed/34572435
http://dx.doi.org/10.3390/biomedicines9091250