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Kynurenine derivative 3-HAA is an agonist ligand for transcription factor YY1

The 3-hydroxyanthranilic acid (3-HAA), a derivative of kynurenine, was reported to suppress tumor growth. However, the function of 3-HAA largely remains unclear. Here, we report that 3-hydroxyanthranilic acid (3-HAA) is lower in tumor cells, while adding exogenous 3-HAA induces apoptosis in hepatoce...

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Detalles Bibliográficos
Autores principales: Shi, Zhaopeng, Gan, Guifang, Xu, Xiang, Zhang, Jieying, Yuan, Yuan, Bi, Bo, Gao, Xianfu, Xu, Pengfei, Zeng, Wenbin, Li, Jixi, Ye, Youqiong, Zhou, Aiwu, Zhang, Naixia, Liu, Wen, Lin, Shuhai, Mi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465765/
https://www.ncbi.nlm.nih.gov/pubmed/34563230
http://dx.doi.org/10.1186/s13045-021-01165-4