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Single cell RNA-seq data and bulk gene profiles reveal a novel signature of disease progression in multiple myeloma

BACKGROUND: The development of multiple myeloma (MM) is considered to involve a multistep transformation process, but the role of cytogenetic abnormalities and molecular alterations in determining the cell fate of multiple myeloma (MM) remains unclear. Here, we have analyzed single cell RNA-seq data...

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Detalles Bibliográficos
Autores principales: Zeng, Zhiyong, Lin, Junfang, Zhang, Kejie, Guo, Xizhe, Zheng, Xiaoqiang, Yang, Apeng, Chen, Junmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465778/
https://www.ncbi.nlm.nih.gov/pubmed/34563174
http://dx.doi.org/10.1186/s12935-021-02190-6