Titration of Androgen Signaling: How Basic Studies Have Informed Clinical Trials Using High-Dose Testosterone Therapy in Castrate-Resistant Prostate Cancer

Since the Nobel Prize-winning work of Huggins, androgen ablation has been a mainstay for treatment of recurrent prostate cancer. While initially effective for most patients, prostate cancers inevitably develop the ability to survive, grow, and metastasize further, despite ongoing androgen suppressio...

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Detalles Bibliográficos
Autores principales: Nordeen, Steven K., Su, Lih-Jen, Osborne, Gregory A., Hayman, Perry M., Orlicky, David J., Wessells, Veronica M., van Bokhoven, Adrie, Flaig, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465783/
https://www.ncbi.nlm.nih.gov/pubmed/34575033
http://dx.doi.org/10.3390/life11090884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465783/
https://www.ncbi.nlm.nih.gov/pubmed/34575033
http://dx.doi.org/10.3390/life11090884

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