Whole Blood Transcriptome Profiling Identifies DNA Replication and Cell Cycle Regulation as Early Marker of Response to Anti-PD-1 in Patients with Urothelial Cancer

SIMPLE SUMMARY: Unfortunately, not all patients with urothelial cancer benefit from checkpoint inhibitors (ICIs). Currently, the first radiological response evaluation is not performed until after 9 to 12 weeks of ICI therapy. Early response biomarkers might enable an early switch to more effective...

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Detalles Bibliográficos
Autores principales: van Wilpe, Sandra, Wosika, Victoria, Ciarloni, Laura, Hosseinian Ehrensberger, Sahar, Jeitziner, Rachel, Angelino, Paolo, Duiveman-de Boer, Tjitske, Koornstra, Rutger H. T., de Vries, I. Jolanda M., Gerritsen, Winald R., Schalken, Jack, Mehra, Niven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465885/
https://www.ncbi.nlm.nih.gov/pubmed/34572887
http://dx.doi.org/10.3390/cancers13184660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465885/
https://www.ncbi.nlm.nih.gov/pubmed/34572887
http://dx.doi.org/10.3390/cancers13184660

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