CDR1 Composition Can Affect Nanobody Recombinant Expression Yields

The isolation of nanobodies from pre-immune libraries by means of biopanning is a straightforward process. Nevertheless, the recovered candidates often require optimization to improve some of their biophysical characteristics. In principle, CDRs are not mutated because they are likely to be part of...

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Detalles Bibliográficos
Autores principales: Orlando, Marco, Fortuna, Sara, Oloketuyi, Sandra, Bajc, Gregor, Goldenzweig, Adi, de Marco, Ario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465892/
https://www.ncbi.nlm.nih.gov/pubmed/34572576
http://dx.doi.org/10.3390/biom11091362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465892/
https://www.ncbi.nlm.nih.gov/pubmed/34572576
http://dx.doi.org/10.3390/biom11091362

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