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CDR1 Composition Can Affect Nanobody Recombinant Expression Yields
The isolation of nanobodies from pre-immune libraries by means of biopanning is a straightforward process. Nevertheless, the recovered candidates often require optimization to improve some of their biophysical characteristics. In principle, CDRs are not mutated because they are likely to be part of...
Autores principales: | Orlando, Marco, Fortuna, Sara, Oloketuyi, Sandra, Bajc, Gregor, Goldenzweig, Adi, de Marco, Ario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465892/ https://www.ncbi.nlm.nih.gov/pubmed/34572576 http://dx.doi.org/10.3390/biom11091362 |
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