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Advanced Molecular Dynamics Approaches to Model a Tertiary Complex APRIL/TACI with Long Glycosaminoglycans

Glycosaminoglycans (GAGs) are linear anionic periodic polysaccharides participating in a number of biologically relevant processes in the extracellular matrix via interactions with their protein targets. Due to their periodicity, conformational flexibility, pseudo-symmetry of the sulfation pattern,...

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Detalles Bibliográficos
Autores principales: Marcisz, Mateusz, Maszota-Zieleniak, Martyna, Huard, Bertrand, Samsonov, Sergey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465899/
https://www.ncbi.nlm.nih.gov/pubmed/34572563
http://dx.doi.org/10.3390/biom11091349