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Iron–Sulfur Cluster Biogenesis as a Critical Target in Cancer

Cancer cells preferentially accumulate iron (Fe) relative to non-malignant cells; however, the underlying rationale remains elusive. Iron–sulfur (Fe–S) clusters are critical cofactors that aid in a wide variety of cellular functions (e.g., DNA metabolism and electron transport). In this article, we...

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Detalles Bibliográficos
Autores principales: Petronek, Michael S., Spitz, Douglas R., Allen, Bryan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465902/
https://www.ncbi.nlm.nih.gov/pubmed/34573089
http://dx.doi.org/10.3390/antiox10091458