Novel A-Ring Chalcone Derivatives of Oleanolic and Ursolic Amides with Anti-Proliferative Effect Mediated through ROS-Triggered Apoptosis

A series of A-ring modified oleanolic and ursolic acid derivatives including C28 amides (3-oxo-C2-nicotinoylidene/furfurylidene, 3β-hydroxy-C2-nicotinoylidene, 3β-nicotinoyloxy-, 2-cyano-3,4-seco-4(23)-ene, indolo-, lactame and azepane) were synthesized and screened for their cytotoxic activity agai...

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Detalles Bibliográficos
Autores principales: Khusnutdinova, Elmira, Petrova, Anastasiya, Zileeva, Zulfia, Kuzmina, Ulyana, Zainullina, Liana, Vakhitova, Yulia, Babkov, Denis, Kazakova, Oxana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465963/
https://www.ncbi.nlm.nih.gov/pubmed/34575964
http://dx.doi.org/10.3390/ijms22189796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8465963/
https://www.ncbi.nlm.nih.gov/pubmed/34575964
http://dx.doi.org/10.3390/ijms22189796

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