Doxycycline Attenuates Cancer Cell Growth by Suppressing NLRP3-Mediated Inflammation

NLR family pyrin domain containing 3 (NLRP3) inflammasome formation is triggered by the damaged mitochondria releasing reactive oxygen species. Doxycycline was shown to regulate inflammation; however, its effect on NLRP3 in cancer remains largely unknown. Therefore, we sought to determine the effect...

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Detalles Bibliográficos
Autores principales: Alsaadi, Mohammad, Tezcan, Gulcin, Garanina, Ekaterina E., Hamza, Shaimaa, McIntyre, Alan, Rizvanov, Albert A., Khaiboullina, Svetlana F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466018/
https://www.ncbi.nlm.nih.gov/pubmed/34577552
http://dx.doi.org/10.3390/ph14090852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466018/
https://www.ncbi.nlm.nih.gov/pubmed/34577552
http://dx.doi.org/10.3390/ph14090852

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