High-Fat Diet Induces Pre-Diabetes and Distinct Sex-Specific Metabolic Alterations in Negr1-Deficient Mice

In the large GWAS studies, NEGR1 gene has been one of the most significant gene loci for body mass phenotype. The purpose of the current study was to clarify the role of NEGR1 in the maintenance of systemic metabolism, including glucose homeostasis, by using both male and female Negr1(−/−) mice rece...

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Detalles Bibliográficos
Autores principales: Kaare, Maria, Mikheim, Kaie, Lilleväli, Kersti, Kilk, Kalle, Jagomäe, Toomas, Leidmaa, Este, Piirsalu, Maria, Porosk, Rando, Singh, Katyayani, Reimets, Riin, Taalberg, Egon, Schäfer, Michael K. E., Plaas, Mario, Vasar, Eero, Philips, Mari-Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466019/
https://www.ncbi.nlm.nih.gov/pubmed/34572334
http://dx.doi.org/10.3390/biomedicines9091148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466019/
https://www.ncbi.nlm.nih.gov/pubmed/34572334
http://dx.doi.org/10.3390/biomedicines9091148

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