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High-Fat Diet Induces Pre-Diabetes and Distinct Sex-Specific Metabolic Alterations in Negr1-Deficient Mice
In the large GWAS studies, NEGR1 gene has been one of the most significant gene loci for body mass phenotype. The purpose of the current study was to clarify the role of NEGR1 in the maintenance of systemic metabolism, including glucose homeostasis, by using both male and female Negr1(−/−) mice rece...
Autores principales: | Kaare, Maria, Mikheim, Kaie, Lilleväli, Kersti, Kilk, Kalle, Jagomäe, Toomas, Leidmaa, Este, Piirsalu, Maria, Porosk, Rando, Singh, Katyayani, Reimets, Riin, Taalberg, Egon, Schäfer, Michael K. E., Plaas, Mario, Vasar, Eero, Philips, Mari-Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466019/ https://www.ncbi.nlm.nih.gov/pubmed/34572334 http://dx.doi.org/10.3390/biomedicines9091148 |
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