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VAV Proteins as Double Agents in Cancer: Oncogenes with Tumor Suppressor Roles
SIMPLE SUMMARY: The role of the VAV family (comprised of VAV1, VAV2, and VAV3) in proactive pathways involved in cell transformation has been historically assumed. Indeed, the discovery of potential gain-of-function VAV1 mutations in specific tumor subtypes reinforced this functional archetype. Cont...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466051/ https://www.ncbi.nlm.nih.gov/pubmed/34571765 http://dx.doi.org/10.3390/biology10090888 |