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VAV Proteins as Double Agents in Cancer: Oncogenes with Tumor Suppressor Roles

SIMPLE SUMMARY: The role of the VAV family (comprised of VAV1, VAV2, and VAV3) in proactive pathways involved in cell transformation has been historically assumed. Indeed, the discovery of potential gain-of-function VAV1 mutations in specific tumor subtypes reinforced this functional archetype. Cont...

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Detalles Bibliográficos
Autores principales: Cuadrado, Myriam, Robles-Valero, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466051/
https://www.ncbi.nlm.nih.gov/pubmed/34571765
http://dx.doi.org/10.3390/biology10090888