The Role of Intracellular Trafficking of Notch Receptors in Ligand-Independent Notch Activation

Aberrant Notch signaling has been found in a broad range of human malignancies. Consequently, small molecule inhibitors and antibodies targeting Notch signaling in human cancers have been developed and tested; however, these have failed due to limited anti-tumor efficacy because of dose-limiting tox...

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Detalles Bibliográficos
Autores principales: Hounjet, Judith, Vooijs, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466058/
https://www.ncbi.nlm.nih.gov/pubmed/34572582
http://dx.doi.org/10.3390/biom11091369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466058/
https://www.ncbi.nlm.nih.gov/pubmed/34572582
http://dx.doi.org/10.3390/biom11091369

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