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ATM’s Role in the Repair of DNA Double-Strand Breaks

Ataxia telangiectasia mutated (ATM) is a central kinase that activates an extensive network of responses to cellular stress via a signaling role. ATM is activated by DNA double strand breaks (DSBs) and by oxidative stress, subsequently phosphorylating a plethora of target proteins. In the last sever...

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Detalles Bibliográficos
Autores principales: Shibata, Atsushi, Jeggo, Penny A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466060/
https://www.ncbi.nlm.nih.gov/pubmed/34573351
http://dx.doi.org/10.3390/genes12091370