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ATM’s Role in the Repair of DNA Double-Strand Breaks
Ataxia telangiectasia mutated (ATM) is a central kinase that activates an extensive network of responses to cellular stress via a signaling role. ATM is activated by DNA double strand breaks (DSBs) and by oxidative stress, subsequently phosphorylating a plethora of target proteins. In the last sever...
Autores principales: | Shibata, Atsushi, Jeggo, Penny A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466060/ https://www.ncbi.nlm.nih.gov/pubmed/34573351 http://dx.doi.org/10.3390/genes12091370 |
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