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PolyPurine Reverse Hoogsteen Hairpins Work as RNA Species for Gene Silencing

PolyPurine Reverse Hoogsteen Hairpins (PPRHs) are gene-silencing DNA-oligonucleotides developed in our laboratory that are formed by two antiparallel polypurine mirror repeat domains bound intramolecularly by Hoogsteen bonds. The aim of this work was to explore the feasibility of using viral vectors...

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Detalles Bibliográficos
Autores principales: Aubets, Eva, Chillon, Miguel, Ciudad, Carlos J., Noé, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466063/
https://www.ncbi.nlm.nih.gov/pubmed/34576188
http://dx.doi.org/10.3390/ijms221810025