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siRNA-Loaded Hydroxyapatite Nanoparticles for KRAS Gene Silencing in Anti-Pancreatic Cancer Therapy

Pancreatic carcinoma (PC) is greatly induced by the KRAS gene mutation, but effective targeted delivery for gene therapy has not existed. Small interfering ribonucleic acid (siRNA) serves as an advanced therapeutic modality and holds great promise for cancer treatment. However, the development of a...

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Detalles Bibliográficos
Autores principales: Luo, Dandan, Xu, Xiaochun, Iqbal, M. Zubair, Zhao, Qingwei, Zhao, Ruibo, Farheen, Jabeen, Zhang, Quan, Zhang, Peiliang, Kong, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466089/
https://www.ncbi.nlm.nih.gov/pubmed/34575504
http://dx.doi.org/10.3390/pharmaceutics13091428