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Anti-Inflammatory Effect of Charantadiol A, Isolated from Wild Bitter Melon Leaf, on Heat-Inactivated Porphyromonas gingivalis-Stimulated THP-1 Monocytes and a Periodontitis Mouse Model

Porphyromonas gingivalis has been identified as one of the major periodontal pathogens. Activity-directed fractionation and purification processes were employed to identify bioactive compounds from bitter melon leaf. Ethanolic extract of bitter melon leaf was separated into five subfractions by open...

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Detalles Bibliográficos
Autores principales: Tsai, Tzung-Hsun, Chang, Chi-I, Hung, Ya-Ling, Huang, Wen-Cheng, Chang, Hsiang, Kuo, Yueh-Hsiung, Chyuan, Jong-Ho, Chuang, Lu-Te, Tsai, Po-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466092/
https://www.ncbi.nlm.nih.gov/pubmed/34577123
http://dx.doi.org/10.3390/molecules26185651