NRF2 Mediates Therapeutic Resistance to Chemoradiation in Colorectal Cancer through a Metabolic Switch

Radiation resistance is a significant clinical problem in rectal cancer treatment, the mechanisms of which are poorly understood. NRF2 signalling is known to contribute to chemo/radioresistance in some cancers, but its role in therapeutic resistance in colorectal cancer (CRC) is unexplored. Using si...

Descripción completa

Detalles Bibliográficos
Autores principales: O’Cathail, Séan M., Wu, Chieh-Hsi, Thomas, Rachael, Hawkins, Maria A., Maughan, Tim S., Lewis, Annabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466195/
https://www.ncbi.nlm.nih.gov/pubmed/34573012
http://dx.doi.org/10.3390/antiox10091380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466195/
https://www.ncbi.nlm.nih.gov/pubmed/34573012
http://dx.doi.org/10.3390/antiox10091380

Ejemplares similares