Mammalian SIRT6 Represses Invasive Cancer Cell Phenotypes through ATP Citrate Lyase (ACLY)-Dependent Histone Acetylation

The modulation of dynamic histone acetylation states is key for organizing chromatin structure and modulating gene expression and is regulated by histone acetyltransferase (HAT) and histone deacetylase (HDAC) enzymes. The mammalian SIRT6 protein, a member of the Class III HDAC Sirtuin family of NAD+...

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Detalles Bibliográficos
Autores principales: Zheng, Wei, Tasselli, Luisa, Li, Tie-mei, Chua, Katrin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466468/
https://www.ncbi.nlm.nih.gov/pubmed/34573442
http://dx.doi.org/10.3390/genes12091460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466468/
https://www.ncbi.nlm.nih.gov/pubmed/34573442
http://dx.doi.org/10.3390/genes12091460

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