A Comparative Endocrine Trans-Differentiation Approach to Pancreatic Ductal Adenocarcinoma Cells with Different EMT Phenotypes Identifies Quasi-Mesenchymal Tumor Cells as Those with Highest Plasticity

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancer types with the quasi-mesenchymal (QM) subtype of PDAC having the worst prognosis. De-differentiation of the ductal tumor cells to a mesenchymal phenotype occurs as a result of epithelial–mesenchymal transition (EM...

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Detalles Bibliográficos
Autores principales: Schmidtlein, Paula M., Volz, Clara, Braun, Rüdiger, Thürling, Isabel, Lapshyna, Olha, Wellner, Ulrich F., Konukiewitz, Björn, Lehnert, Hendrik, Marquardt, Jens-Uwe, Ungefroren, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466512/
https://www.ncbi.nlm.nih.gov/pubmed/34572891
http://dx.doi.org/10.3390/cancers13184663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466512/
https://www.ncbi.nlm.nih.gov/pubmed/34572891
http://dx.doi.org/10.3390/cancers13184663

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