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A Comparative Endocrine Trans-Differentiation Approach to Pancreatic Ductal Adenocarcinoma Cells with Different EMT Phenotypes Identifies Quasi-Mesenchymal Tumor Cells as Those with Highest Plasticity

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancer types with the quasi-mesenchymal (QM) subtype of PDAC having the worst prognosis. De-differentiation of the ductal tumor cells to a mesenchymal phenotype occurs as a result of epithelial–mesenchymal transition (EM...

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Detalles Bibliográficos
Autores principales:	Schmidtlein, Paula M., Volz, Clara, Braun, Rüdiger, Thürling, Isabel, Lapshyna, Olha, Wellner, Ulrich F., Konukiewitz, Björn, Lehnert, Hendrik, Marquardt, Jens-Uwe, Ungefroren, Hendrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466512/ https://www.ncbi.nlm.nih.gov/pubmed/34572891 http://dx.doi.org/10.3390/cancers13184663

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