The Role of Smoothened-Dependent and -Independent Hedgehog Signaling Pathway in Tumorigenesis

The Hedgehog (Hh)-glioma-associated oncogene homolog (GLI) signaling pathway is highly conserved among mammals, with crucial roles in regulating embryonic development as well as in cancer initiation and progression. The GLI transcription factors (GLI1, GLI2, and GLI3) are effectors of the Hh pathway...

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Detalles Bibliográficos
Autores principales: Chai, Jian Yi, Sugumar, Vaisnevee, Alshawsh, Mohammed Abdullah, Wong, Won Fen, Arya, Aditya, Chong, Pei Pei, Looi, Chung Yeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466551/
https://www.ncbi.nlm.nih.gov/pubmed/34572373
http://dx.doi.org/10.3390/biomedicines9091188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466551/
https://www.ncbi.nlm.nih.gov/pubmed/34572373
http://dx.doi.org/10.3390/biomedicines9091188

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