Virtual Alanine Scan of the Main Protease Active Site in Severe Acute Respiratory Syndrome Coronavirus 2

Recently, inhibitors of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) have been proposed as potential therapeutic agents for COVID-19. Studying effects of amino acid mutations in the conformation of drug targets is necessary for anticipating drug resistance. I...

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Detalles Bibliográficos
Autores principales: Nakayoshi, Tomoki, Kato, Koichi, Kurimoto, Eiji, Oda, Akifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466562/
https://www.ncbi.nlm.nih.gov/pubmed/34576002
http://dx.doi.org/10.3390/ijms22189837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466562/
https://www.ncbi.nlm.nih.gov/pubmed/34576002
http://dx.doi.org/10.3390/ijms22189837

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