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Insights into Comparative Modeling of V(H)H Domains

In the particular case of the Camelidae family, immunoglobulin proteins have evolved into a unique and more simplified architecture with only heavy chains. The variable domains of these chains, named V(H)Hs, have a number of Complementary Determining Regions (CDRs) reduced by half, and can function...

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Detalles Bibliográficos
Autores principales: Vattekatte, Akhila Melarkode, Cadet, Frédéric, Gelly, Jean-Christophe, de Brevern, Alexandre G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466624/
https://www.ncbi.nlm.nih.gov/pubmed/34575931
http://dx.doi.org/10.3390/ijms22189771