Salubrinal Enhances Cancer Cell Death during Glucose Deprivation through the Upregulation of xCT and Mitochondrial Oxidative Stress

Cancer cells have the metabolic flexibility to adapt to heterogeneous tumor microenvironments. The integrated stress response (ISR) regulates the cellular adaptation response during nutrient stress. However, the issue of how the ISR regulates metabolic flexibility is still poorly understood. In this...

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Detalles Bibliográficos
Autores principales: Chen, Mei-Chun, Hsu, Li-Lin, Wang, Sheng-Fan, Pan, Yi-Ling, Lo, Jeng-Fan, Yeh, Tien-Shun, Tseng, Ling-Ming, Lee, Hsin-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466651/
https://www.ncbi.nlm.nih.gov/pubmed/34572286
http://dx.doi.org/10.3390/biomedicines9091101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466651/
https://www.ncbi.nlm.nih.gov/pubmed/34572286
http://dx.doi.org/10.3390/biomedicines9091101

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