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Maternal Under- and Over-Nutrition during Gestation Causes Islet Hypertrophy and Sex-Specific Changes to Pancreas DNA Methylation in Fetal Sheep

SIMPLE SUMMARY: The development of the fetal pancreas tissue can be affected during gestation by alterations to the intrauterine environment, often referred to as fetal programming. However, the mechanisms by which fetal programming predisposes offspring to reduced β-cell function later in life are...

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Detalles Bibliográficos
Autores principales: Peterson, Maria, Gauvin, Mary, Pillai, Sambhu, Jones, Amanda, McFadden, Katelyn, Cameron, Katelynn, Reed, Sarah, Zinn, Steven, Govoni, Kristen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466738/
https://www.ncbi.nlm.nih.gov/pubmed/34573497
http://dx.doi.org/10.3390/ani11092531