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Gene Duplication and Gene Fusion Are Important Drivers of Tumourigenesis during Cancer Evolution
Chromosomal rearrangement and genome instability are common features of cancer cells in human. Consequently, gene duplication and gene fusion events are frequently observed in human malignancies and many of the products of these events are pathogenic, representing significant drivers of tumourigenes...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466788/ https://www.ncbi.nlm.nih.gov/pubmed/34573358 http://dx.doi.org/10.3390/genes12091376 |