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Gene Duplication and Gene Fusion Are Important Drivers of Tumourigenesis during Cancer Evolution

Chromosomal rearrangement and genome instability are common features of cancer cells in human. Consequently, gene duplication and gene fusion events are frequently observed in human malignancies and many of the products of these events are pathogenic, representing significant drivers of tumourigenes...

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Detalles Bibliográficos
Autores principales: Glenfield, Cian, Innan, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466788/
https://www.ncbi.nlm.nih.gov/pubmed/34573358
http://dx.doi.org/10.3390/genes12091376