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Lignosulfonic Acid Sodium Is a Noncompetitive Inhibitor of Human Factor XIa

The anticoagulant activity of lignosulfonic acid sodium (LSAS), a non-saccharide heparin mimetic, was investigated in this study. LSAS is a relatively safe industrial byproduct with similar polyanionic characteristics to that of heparin. Human plasma clotting assays, fibrin polymerization testing, a...

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Detalles Bibliográficos
Autores principales: Kar, Srabani, Bankston, Page, Afosah, Daniel K., Al-Horani, Rami A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466798/
https://www.ncbi.nlm.nih.gov/pubmed/34577586
http://dx.doi.org/10.3390/ph14090886