Quinacrine Induces Nucleolar Stress in Treatment-Refractory Ovarian Cancer Cell Lines

SIMPLE SUMMARY: A high mortality rate in ovarian cancer imposes the need for improved therapy; most patients initially respond to systemic chemotherapy but later relapse with fatal treatment-refractory tumors. We previously evaluated repurposing the antimalarial agent quinacrine as an anticancer age...

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Detalles Bibliográficos
Autores principales: Oien, Derek B., Ray, Upasana, Pathoulas, Christopher L., Jin, Ling, Thirusangu, Prabhu, Jung, Deokbeom, Kumka, Joseph E., Xiao, Yinan, Sarkar Bhattacharya, Sayantani, Montoya, Dennis, Chien, Jeremy, Shridhar, Viji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466834/
https://www.ncbi.nlm.nih.gov/pubmed/34572872
http://dx.doi.org/10.3390/cancers13184645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466834/
https://www.ncbi.nlm.nih.gov/pubmed/34572872
http://dx.doi.org/10.3390/cancers13184645

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