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Quinacrine Induces Nucleolar Stress in Treatment-Refractory Ovarian Cancer Cell Lines
SIMPLE SUMMARY: A high mortality rate in ovarian cancer imposes the need for improved therapy; most patients initially respond to systemic chemotherapy but later relapse with fatal treatment-refractory tumors. We previously evaluated repurposing the antimalarial agent quinacrine as an anticancer age...
Autores principales: | Oien, Derek B., Ray, Upasana, Pathoulas, Christopher L., Jin, Ling, Thirusangu, Prabhu, Jung, Deokbeom, Kumka, Joseph E., Xiao, Yinan, Sarkar Bhattacharya, Sayantani, Montoya, Dennis, Chien, Jeremy, Shridhar, Viji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466834/ https://www.ncbi.nlm.nih.gov/pubmed/34572872 http://dx.doi.org/10.3390/cancers13184645 |
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