Intranasal Delivery of RGD-Containing Osteopontin Heptamer Peptide Confers Neuroprotection in the Ischemic Brain and Augments Microglia M2 Polarization

Osteopontin (OPN), a phosphorylated glycoprotein, is induced in response to tissue damage and inflammation in various organs, including the brain. In our previous studies, we reported the robust neuroprotective effects of the icosamer OPN peptide OPNpt20, containing arginine-glycine-aspartic acid (R...

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Detalles Bibliográficos
Autores principales: Davaanyam, Dashdulam, Kim, Il-Doo, Lee, Ja-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466884/
https://www.ncbi.nlm.nih.gov/pubmed/34576163
http://dx.doi.org/10.3390/ijms22189999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466884/
https://www.ncbi.nlm.nih.gov/pubmed/34576163
http://dx.doi.org/10.3390/ijms22189999

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