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Hypoblast Formation in Bovine Embryos Does Not Depend on NANOG

The role of the pluripotency factor NANOG during the second embryonic lineage differentiation has been studied extensively in mouse, although species-specific differences exist. To elucidate the role of NANOG in an alternative model organism, we knocked out NANOG in fibroblast cells and produced bov...

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Detalles Bibliográficos
Autores principales: Springer, Claudia, Zakhartchenko, Valeri, Wolf, Eckhard, Simmet, Kilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8466907/
https://www.ncbi.nlm.nih.gov/pubmed/34571882
http://dx.doi.org/10.3390/cells10092232