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Developing an Updated Strategy for Estimating the Free-Energy Parameters in RNA Duplexes
For the last 20 years, it has been common lore that the free energy of RNA duplexes formed from canonical Watson–Crick base pairs (bps) can be largely approximated with dinucleotide bp parameters and a few simple corrective constants that are duplex independent. Additionally, the standard benchmark...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467000/ https://www.ncbi.nlm.nih.gov/pubmed/34575896 http://dx.doi.org/10.3390/ijms22189708 |