The Effect of a Synthetic Estrogen, Ethinylestradiol, on the hERG Block by E-4031

Inhibition of K(+)-conductance through the human ether-a-go-go related gene (hERG) channel leads to QT prolongation and is associated with cardiac arrhythmias. We previously reported that physiological concentrations of some estrogens partially suppress the hERG channel currents by interacting with...

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Detalles Bibliográficos
Autores principales: Tamura, Fumiya, Sugimoto, Shintaro, Sugimoto, Mana, Sakamoto, Kazuho, Yamaguchi, Masahiko, Suzuki, Takeshi, Fukuda, Keiichi, Ieda, Masaki, Kurokawa, Junko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467063/
https://www.ncbi.nlm.nih.gov/pubmed/34572598
http://dx.doi.org/10.3390/biom11091385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467063/
https://www.ncbi.nlm.nih.gov/pubmed/34572598
http://dx.doi.org/10.3390/biom11091385

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