Dual-Specificity Phosphatase 1 (DUSP1) Has a Central Role in Redox Homeostasis and Inflammation in the Mouse Cochlea

Stress-activated protein kinases (SAPK) are associated with sensorineural hearing loss (SNHL) of multiple etiologies. Their activity is tightly regulated by dual-specificity phosphatase 1 (DUSP1), whose loss of function leads to sustained SAPK activation. Dusp1 gene knockout in mice accelerates SNHL...

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Detalles Bibliográficos
Autores principales: Bermúdez-Muñoz, Jose M., Celaya, Adelaida M., García-Mato, Ángela, Muñoz-Espín, Daniel, Rodríguez-de la Rosa, Lourdes, Serrano, Manuel, Varela-Nieto, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467085/
https://www.ncbi.nlm.nih.gov/pubmed/34572983
http://dx.doi.org/10.3390/antiox10091351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467085/
https://www.ncbi.nlm.nih.gov/pubmed/34572983
http://dx.doi.org/10.3390/antiox10091351

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