Novel Ferrocene Derivatives Induce Apoptosis through Mitochondria-Dependent and Cell Cycle Arrest via PI3K/Akt/mTOR Signaling Pathway in T Cell Acute Lymphoblastic Leukemia

SIMPLE SUMMARY: T cell acute lymphoblastic leukemia (T-ALL) is a malignant hematologic disease that urgently requires efficient therapeutic agents. The aim of this study is to explore the anti-T-ALL activity of novel ferrocene derivatives. It was found that ferrocene derivatives F1–F7 synthesized by...

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Detalles Bibliográficos
Autores principales: Zeng, Liao, Tang, Mingqing, Pi, Chao, Zheng, Jianrong, Gao, Sanxing, Chabanne, Titaua, Chauvin, Remi, Cheng, Wenzhao, Lin, Hongjun, Xu, Ruian, Cui, Xiuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467123/
https://www.ncbi.nlm.nih.gov/pubmed/34572904
http://dx.doi.org/10.3390/cancers13184677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467123/
https://www.ncbi.nlm.nih.gov/pubmed/34572904
http://dx.doi.org/10.3390/cancers13184677

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