An in vivo pharmacokinetic study of metformin microparticles as an oral sustained release formulation in rabbits

BACKGROUND: Metformin hydrochloride is a biguanide derivative that has been widely used to treat type 2 diabetes in humans. In veterinary medicine, metformin has shown increasing potential for diabetes treatment in different species, such as equids, dogs, cats and rabbits. It is highly hydrophilic,...

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Detalles Bibliográficos
Autores principales: Bouriche, Sihem, Alonso-García, Angela, Cárceles-Rodríguez, Carlos M., Rezgui, Farouk, Fernández-Varón, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467142/
https://www.ncbi.nlm.nih.gov/pubmed/34563196
http://dx.doi.org/10.1186/s12917-021-03016-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467142/
https://www.ncbi.nlm.nih.gov/pubmed/34563196
http://dx.doi.org/10.1186/s12917-021-03016-3

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