Blockade of Serotonin 5-HT(6) Receptor Constitutive Activity Alleviates Cognitive Deficits in a Preclinical Model of Neurofibromatosis Type 1

Neurofibromatosis type 1 (NF1) is a common inherited disorder caused by mutations of the NF1 gene that encodes the Ras-GTPase activating protein neurofibromin, leading to overactivation of Ras-dependent signaling pathways such as the mTOR pathway. It is often characterized by a broad range of cognit...

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Detalles Bibliográficos
Autores principales: Doucet, Emilie, Grychowska, Katarzyna, Zajdel, Pawel, Bockaert, Joël, Marin, Philippe, Bécamel, Carine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467191/
https://www.ncbi.nlm.nih.gov/pubmed/34576341
http://dx.doi.org/10.3390/ijms221810178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467191/
https://www.ncbi.nlm.nih.gov/pubmed/34576341
http://dx.doi.org/10.3390/ijms221810178

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