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Insights into the Interaction of Lysosomal Amino Acid Transporters SLC38A9 and SLC36A1 Involved in mTORC1 Signaling in C2C12 Cells

Amino acids are critical for mammalian target of rapamycin complex 1 (mTORC1) activation on the lysosomal surface. Amino acid transporters SLC38A9 and SLC36A1 are the members of the lysosomal amino acid sensing machinery that activates mTORC1. The current study aims to clarify the interaction of SLC...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Wan, Xuebin, Du, Xiaoli, Zhong, Zhuxia, Peng, Jian, Xiong, Qi, Chai, Jin, Jiang, Siwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467208/
https://www.ncbi.nlm.nih.gov/pubmed/34572527
http://dx.doi.org/10.3390/biom11091314