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Revealing the Mutation Patterns of Drug-Resistant Reverse Transcriptase Variants of Human Immunodeficiency Virus through Proteochemometric Modeling

Drug-resistant cases of human immunodeficiency virus (HIV) nucleoside reverse transcriptase inhibitors (NRTI) are constantly accumulating due to the frequent mutations of the reverse transcriptase (RT). Predicting the potential drug resistance of HIV-1 NRTIs could provide instructions for the proper...

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Detalles Bibliográficos
Autores principales: Qiu, Jingxuan, Tian, Xinxin, Liu, Jiangru, Qin, Yulong, Zhu, Junjie, Xu, Dongpo, Qiu, Tianyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8467226/
https://www.ncbi.nlm.nih.gov/pubmed/34572515
http://dx.doi.org/10.3390/biom11091302